Monday, 26 December 2011

Cataplexy Medications


Definition of Cataplexy: Cataplexy is a sudden loss of muscle tone, sometimes associated with narcolepsy.

Drugs associated with Cataplexy

The following drugs and medications are in some way related to, or used in the treatment of Cataplexy. This service should be used as a supplement to, and NOT a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.





Drug List:

Sunday, 25 December 2011

Finastid




Finastid may be available in the countries listed below.


Ingredient matches for Finastid



Finasteride

Finasteride is reported as an ingredient of Finastid in the following countries:


  • Italy

International Drug Name Search

Saturday, 24 December 2011

Dantrolène




Dantrolène may be available in the countries listed below.


Ingredient matches for Dantrolène



Dantrolene

Dantrolène (DCF) is known as Dantrolene in the US.

International Drug Name Search

Glossary

DCFDénomination Commune Française

Click for further information on drug naming conventions and International Nonproprietary Names.

Thursday, 22 December 2011

Mannit Fresenius




Mannit Fresenius may be available in the countries listed below.


Ingredient matches for Mannit Fresenius



Mannitol

Mannitol is reported as an ingredient of Mannit Fresenius in the following countries:


  • Austria

International Drug Name Search

Wednesday, 21 December 2011

Morantel Citrate




Morantel Citrate may be available in the countries listed below.


Ingredient matches for Morantel Citrate



Morantel

Morantel Citrate (BANM) is also known as Morantel (Prop.INN)

International Drug Name Search

Glossary

BANMBritish Approved Name (Modified)
Prop.INNProposed International Nonproprietary Name (World Health Organization)

Click for further information on drug naming conventions and International Nonproprietary Names.

Tuesday, 20 December 2011

Tifol




Tifol may be available in the countries listed below.


Ingredient matches for Tifol



Folic Acid

Folic Acid sodium salt (a derivative of Folic Acid) is reported as an ingredient of Tifol in the following countries:


  • Slovenia

International Drug Name Search

Mébévérine Zydus




Mébévérine Zydus may be available in the countries listed below.


Ingredient matches for Mébévérine Zydus



Mebeverine

Mebeverine hydrochloride (a derivative of Mebeverine) is reported as an ingredient of Mébévérine Zydus in the following countries:


  • France

International Drug Name Search

Friday, 16 December 2011

Kapril




Kapril may be available in the countries listed below.


Ingredient matches for Kapril



Captopril

Captopril is reported as an ingredient of Kapril in the following countries:


  • Bosnia & Herzegowina

  • Turkey

International Drug Name Search

Wednesday, 14 December 2011

belimumab


Generic Name: belimumab (be LIM ue mab)

Brand Names: Benlysta


What is belimumab?

Belimumab is a monoclonal antibody that affects the actions of the body's immune system. Monoclonal antibodies are made to target and destroy only certain cells in the body. This may help to protect healthy cells from damage.


Belimumab is used in to treat active systemic lupus erythematosus (SLE) in adults.


Belimumab is not for use in people who have severe kidney problems caused by SLE, or have active SLE that affects the central nervous system (brain, nerves, and spinal cord).


Belimumab may also be used for other purposes not listed in this medication guide.


What is the most important information I should know about belimumab?


You should not use belimumab if you are allergic to it.

Before you receive belimumab, tell your doctor if you have an active or chronic infection, a history of cancer, or a history of depression or mental illness.


Serious and sometimes fatal infections may occur during treatment with belimumab. Call your doctor right away if you have signs of infection such as fever, chills, flu symptoms, night sweats, pain or burning when you urinate, cough with mucus, stabbing chest pain, feeling short of breath, bloody diarrhea, or swelling, pain, tenderness, or redness anywhere on your body. Belimumab can lower blood cells that help your body fight infections. Your blood may need to be tested often. Avoid being near people who are sick or have infections.

Avoid being near people who have colds, the flu, or other contagious illnesses. Contact your doctor at once if you develop signs of infection. Do not receive a "live" vaccine within 30 days before or after you are treated with belimumab.


You may have thoughts about suicide while receiving belimumab, especially if you have a history of suicidal thoughts or actions. Report any new or worsening symptoms to your doctor, such as: depression, anxiety, mood or behavior changes, trouble sleeping, or thoughts about hurting yourself or others.


What should I discuss with my healthcare provider before receiving belimumab?


You should not use belimumab if you are allergic to it.

To make sure you can safely receive belimumab, tell your doctor if you have any of these other conditions:



  • an active or chronic infection;




  • a history of cancer; or




  • a history of depression or mental illness.



You may have thoughts about suicide while receiving belimumab, especially if you have a history of suicidal thoughts or actions.


FDA pregnancy category C. It is not known whether belimumab will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. If you are pregnant, your name may be listed on a pregnancy registry. This is to track the outcome of the pregnancy and to evaluate any effects of belimumab on the baby. It is not known whether belimumab passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are using belimumab.

How is belimumab given?


Belimumab is injected into a vein through an IV. You will receive this injection in a clinic or hospital setting. Belimumab must be given slowly, and the IV infusion can take about an hour to complete.


The first 3 doses of belimumab are given 2 weeks apart. Then the injections are given every 4 weeks. Your dosing schedule may be different. Follow your doctor's instructions.


You may be given other medications to prevent certain side effects of belimumab.

What happens if I miss a dose?


Contact your doctor if you miss an appointment for your belimumab injection.


What happens if I overdose?


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while receiving belimumab?


Avoid being near people who have colds, the flu, or other contagious illnesses.


Do not receive a "live" vaccine while you are being treated with belimumab. The vaccine may not work as well during this time, and may not fully protect you from disease. Live vaccines include measles, mumps, rubella (MMR), Bacillus Calmette-Guérin (BCG), oral polio, rotavirus, smallpox, typhoid, yellow fever, varicella (chickenpox), H1N1 influenza, and nasal flu vaccine.

Belimumab side effects


Some people receiving a belimumab injection have had a reaction to the infusion (when the medicine is injected into the vein). Tell your caregiver right away if you feel nauseated, light-headed, itchy, or have muscle pain, severe headache, or slow heartbeats. Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have a serious side effect such as:

  • new or worsening depression, anxiety, mood or behavior changes, trouble sleeping, or thoughts about hurting yourself or others;




  • chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling.




  • wheezing, chest tightness, trouble breathing; or




Serious and sometimes fatal infections may occur during treatment with belimumab. Call your doctor right away if you have signs of infection such as:

  • fever, chills, flu symptoms, night sweats, weight loss;




  • increased urination, pain or burning when you urinate;




  • cough with yellow or green mucus, stabbing chest pain, feeling short of breath;




  • swelling, pain, tenderness, or redness anywhere on your body; or




  • bloody diarrhea.



Less serious side effects may include:



  • nausea, diarrhea, stomach pain;




  • mild pain in your arms or legs; or




  • mild cold symptoms such as stuffy nose, sneezing, sore throat.



This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


Belimumab Dosing Information


Usual Adult Dose for Systemic Lupus Erythematosus:

10 mg/kg as an intravenous infusion only, over a period of 1 hour, at 2 week intervals for the first 3 doses and at 4 week intervals thereafter.

Consider administering premedication for prophylaxis against infusion reactions and hypersensitivity reactions.


What other drugs will affect belimumab?


Tell your doctor about all other medicines you use, especially:



  • cyclophosphamide (Cytoxan); or




  • drugs that weaken your immune system such as cancer medicine, steroids, and medicines to prevent rejection of a transplanted organ.



This list is not complete and other drugs may interact with belimumab. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.



More belimumab resources


  • Belimumab Side Effects (in more detail)
  • Belimumab Dosage
  • Belimumab Use in Pregnancy & Breastfeeding
  • Belimumab Drug Interactions
  • Belimumab Support Group
  • 0 Reviews for Belimumab - Add your own review/rating


  • belimumab Intravenous Advanced Consumer (Micromedex) - Includes Dosage Information

  • Belimumab Professional Patient Advice (Wolters Kluwer)

  • Belimumab MedFacts Consumer Leaflet (Wolters Kluwer)

  • Benlysta Prescribing Information (FDA)

  • Benlysta Consumer Overview



Compare belimumab with other medications


  • Systemic Lupus Erythematosus


Where can I get more information?


  • Your doctor or pharmacist can provide more information about belimumab.

See also: belimumab side effects (in more detail)


Friday, 9 December 2011

Monotrate




Monotrate may be available in the countries listed below.


Ingredient matches for Monotrate



Isosorbide Mononitrate

Isosorbide Mononitrate is reported as an ingredient of Monotrate in the following countries:


  • Bangladesh

  • India

  • Myanmar

  • Sri Lanka

International Drug Name Search

Coartem


Coartem is a brand name of artemether/lumefantrine, approved by the FDA in the following formulation(s):


COARTEM (artemether; lumefantrine - tablet; oral)



  • Manufacturer: NOVARTIS

    Approval date: April 7, 2009

    Strength(s): 20MG;120MG [RLD]

Has a generic version of Coartem been approved?


No. There is currently no therapeutically equivalent version of Coartem available.


Note: Fraudulent online pharmacies may attempt to sell an illegal generic version of Coartem. These medications may be counterfeit and potentially unsafe. If you purchase medications online, be sure you are buying from a reputable and valid online pharmacy. Ask your health care provider for advice if you are unsure about the online purchase of any medication.

See also: About generic drugs.




Related Patents


Patents are granted by the U.S. Patent and Trademark Office at any time during a drug's development and may include a wide range of claims.




  • Antimalarial compositions
    Patent 5,677,331
    Issued: October 14, 1997
    Inventor(s): Zhou; Yiqing & Ning; Dianxi & Wang; Shufen & Ding; Deben & Li; Guofu & Shan; Chengqi & Liu; Guangyu
    Assignee(s): Ciba-Geigy AG
    Institute of Microbiology and Epidemiology, Academy of Military Medical
    The invention relates to a synergistic antimalarial composition which comprises the antimalarial agent benflumetol and also an antimalarial agent from the artemisinine group such as artemether. The composition can be formulated into solid dosage forms such as tablets and is useful for the treatment of drug resistant malaria.
    Patent expiration dates:

    • October 14, 2014
      ✓ 
      Patent use: TREATMENT OF ACUTE, UNCOMPLICATED MALARIA INFECTION DUE TO PLASMODIUM FALCIPARUM IN PATIENTS OF 5KG BODYWEIGHT AND ABOVE
      ✓ 
      Drug product



Related Exclusivities

Exclusivity is exclusive marketing rights granted by the FDA upon approval of a drug and can run concurrently with a patent or not. Exclusivity is a statutory provision and is granted to an NDA applicant if statutory requirements are met.

  • Exclusivity expiration dates:
    • April 7, 2014 - NEW CHEMICAL ENTITY

    • April 7, 2016 - ORPHAN DRUG EXCLUSIVITY

See also...

  • Coartem Consumer Information (Drugs.com)
  • Coartem Consumer Information (Wolters Kluwer)
  • Coartem Consumer Information (Cerner Multum)
  • Coartem Advanced Consumer Information (Micromedex)
  • Coartem AHFS DI Monographs (ASHP)
  • Artemether/Lumefantrine Consumer Information (Wolters Kluwer)
  • Artemether and lumefantrine Consumer Information (Cerner Multum)
  • Artemether and lumefantrine Advanced Consumer Information (Micromedex)
  • Artemether and Lumefantrine AHFS DI Monographs (ASHP)

Thursday, 8 December 2011

Isotic Azora




Isotic Azora may be available in the countries listed below.


Ingredient matches for Isotic Azora



Naphazoline

Naphazoline hydrochloride (a derivative of Naphazoline) is reported as an ingredient of Isotic Azora in the following countries:


  • Indonesia

Pheniramine

Pheniramine maleate (a derivative of Pheniramine) is reported as an ingredient of Isotic Azora in the following countries:


  • Indonesia

International Drug Name Search

Sunday, 4 December 2011

Sefanid




Sefanid may be available in the countries listed below.


Ingredient matches for Sefanid



Cefadroxil

Cefadroxil is reported as an ingredient of Sefanid in the following countries:


  • Bangladesh

International Drug Name Search

Saturday, 3 December 2011

Neofomiral




Neofomiral may be available in the countries listed below.


Ingredient matches for Neofomiral



Fluconazole

Fluconazole is reported as an ingredient of Neofomiral in the following countries:


  • Mexico

International Drug Name Search

Friday, 2 December 2011

Magnecyl-koffein brus




Magnecyl-koffein brus may be available in the countries listed below.


Ingredient matches for Magnecyl-koffein brus



Aspirin

Acetylsalicylic Acid is reported as an ingredient of Magnecyl-koffein brus in the following countries:


  • Sweden

Caffeine

Caffeine is reported as an ingredient of Magnecyl-koffein brus in the following countries:


  • Sweden

International Drug Name Search